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Article

The binding and structural basis of fox ACE2 to RBDs from different sarbecoviruses.

Virologica Sinica - 1 Aug 2024

Chen Junsen, Sun Junqing, Xu Zepeng, Li Linjie, Kang Xinrui, Luo Chunliang, Wang Qi, Guo Xueyang, Li Yan, Liu Kefang, Wu Ying

Abstract excerpt

Foxes are susceptible to SARS-CoV-2 in laboratory settings, and there have also been reports of natural infections of both SARS-CoV and SARS-CoV-2 in foxes. In this study, we assessed the binding capacities of fox ACE2 to important sarbecoviruses, including SARS-CoV, SARS-CoV-2, and animal-origin SARS-CoV-2 related viruses. Our findings demonstrated that fox ACE2 exhibits broad binding capabilities to...

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Identifiers

PMID: 38866203
DOI: 10.1016/j.virs.2024.06.004
PMCID: PMC11401476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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