Article
Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nature communications - 21 Jul 2023
Zhao Zhennan, Xie Yufeng, Bai Bin, Luo Chunliang, Zhou Jingya, Li Weiwei, Meng Yumin, Li Linjie, Li Dedong, Li Xiaomei, Li Xiaoxiong, Wang Xiaoyun, Sun Junqing, Xu Zepeng, Sun Yeping, Zhang Wei, Fan Zheng, Zhao Xin, Wu Linhuan, Ma Juncai, Li Odel Y, Shang Guijun, Chai Yan, Liu Kefang, Wang Peiyi, Gao George F, Qi Jianxun
Abstract excerpt
Multiple SARS-CoV-2 Omicron sub-variants, such as BA.2, BA.2.12.1, BA.4, and BA.5, emerge one after another. BA.5 has become the dominant strain worldwide. Additionally, BA.2.75 is significantly increasing in some countries. Exploring their receptor binding and interspecies transmission risk is urgently needed. Herein, we examine the binding capacities of human and other 28 animal ACE2 orthologs covering nine...
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