Article
Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants.
Nature communications - 20 Oct 2021
Han Pengcheng, Su Chao, Zhang Yanfang, Bai Chongzhi, Zheng Anqi, Qiao Chengpeng, Wang Qing, Niu Sheng, Chen Qian, Zhang Yuqin, Li Weiwei, Liao Hanyi, Li Jing, Zhang Zengyuan, Cho Heecheol, Yang Mengsu, Rong Xiaoyu, Hu Yu, Huang Niu, Yan Jinghua, Wang Qihui, Zhao Xin, Gao George Fu, Qi Jianxun
Abstract excerpt
Multiple SARS-CoV-2 variants of concern (VOCs) have been emerging and some have been linked to an increase in case numbers globally. However, there is yet a lack of understanding of the molecular basis for the interactions between the human ACE2 (hACE2) receptor and these VOCs. Here we examined several VOCs including Alpha, Beta, and Gamma, and demonstrate that five variants receptor-binding domain (RBD)...
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