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Article

Magnetically Guided Adeno‐Associated Virus Delivery for the Spatially Targeted Transduction of Retina in Eyes

7 Jun 2024

Abstract excerpt

Adeno-associated viruses (AAVs) are intensively explored for gene therapies in general and have found promising applications for treating retina diseases. However, controlling the specificity (tropism) and delivery of AAVs to selected layers, cell types, and areas of the retina is a major challenge to further develop retinal gene therapies. Magnetic nanoparticles (MNPs) provide effective delivery platforms to...

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PMID: 38848510
DOI: 10.1002/adhm.202401577

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