Article
Adeno-associated viral vectors for retinal gene transfer and treatment of retinal diseases.
Current gene therapy - 1 Jun 2005
Auricchio Alberto, Rolling Fabienne
Abstract excerpt
Retinal gene transfer holds big promises for the treatment of inherited and non-inherited blinding diseases, such as retinitis pigmentosa or age-related macular degeneration. Key to the development of successful gene-based therapies for the eye are efficient tools for retinal gene transfer. Vectors based on adeno-associated viruses (AAV) are able to transduce robustly and persistently different retinal cell types...
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