Article
Higher Genetic Risk for Type 2 Diabetes Is Associated With a Faster Decline of β-Cell Function in an East Asian Population.
Diabetes care - 1 Aug 2024
Lee Hyunsuk, Choi Jaewon, Kim Jong-Il, Watanabe Richard M, Cho Nam H, Park Kyong Soo, Kwak Soo Heon
Abstract excerpt
OBJECTIVE: While most genetic variants of type 2 diabetes (T2D) are suggested to be associated with β-cell dysfunction cross sectionally, their association with the longitudinal change of β-cell function remains largely unknown. RESEARCH DESIGN AND METHODS: We analyzed data from 6,311 participants without T2D at baseline (mean [SD] age 51.6 [8.7] years) from a community-based prospective cohort in Korea....
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