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Article

The 14-year cumulative genetic high blood pressure and risk of type 2 diabetes in Korean: observational and Mendelian randomization evidence.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Apr 2025

Jeon Jooeun, Jung Keum Ji, Kimm Heejin, Lee Ji-Young, Nam Chung-Mo, Jee Sun Ha

Abstract excerpt

This study aims to evaluate the causal association of blood pressure (BP) with type 2 diabetes (T2D) and assess the cumulative effect of genetic predisposition of high BP or glycemic for future clinical in Korea. To assess the bidirectional causal association between fasting blood sugar (FBS) and systolic blood pressure (SBP) in the large biobank, five MR methods (a 2-stage least squares (2SLS) regression,...

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Identifiers

PMID: 39939824
DOI: 10.1038/s41440-025-02099-x
PMCID: PMC11972959

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