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Article

High genetic risk scores for impaired insulin secretory capacity doubles the risk for type 2 diabetes in Asians and is exacerbated by Western-type diets.

Diabetes/metabolism research and reviews - 1 Jan 2018

Kim Da Sol, Kim Byoung Chul, Daily James W, Park Sunmin

Abstract excerpt

BACKGROUND: Asians have among the highest incidence of type 2 diabetes (T2DM) in the world, partly due to low β-cell function, causing them to rapidly develop T2DM when insulin resistant. This study tested the hypothesis that genetic polymorphisms are responsible for the low β-cell function and that dietary factors interact with the genes to exacerbate their risk of T2DM. METHODS: We selected 10 genetic variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29048714
DOI: 10.1002/dmrr.2944

Genes

ABCA1
CDKAL1
HHEX
IDE
KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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