Article
Causal Effect of the 25-Hydroxyvitamin D Concentration on Cerebral Small Vessel Disease: A Mendelian Randomization Study.
Stroke - 1 Sept 2023
Lee Keon-Joo, Kim Hakyung, Lee Soo Ji, Duperron Marie-Gabrielle, Debette Stéphanie, Bae Hee-Joon, Sung Joohon
Abstract excerpt
BACKGROUND: Previous observational studies reported that a lower serum 25-hydroxyvitamin D [25(OH)D] concentration is associated with a higher burden of cerebral small vessel disease (cSVD). The causality of this association is uncertain, but it would be clinically important, given that 25(OH)D can be a target for intervention. We tried to examine the causal effect of 25(OH)D concentration on cSVD-related...
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