Causal relationship between inflammatory factors and cerebral small vessel disease: Univariate, multivariate, and summary‐data‐based mendelian randomization analysis

Abstract excerpt

OBJECTIVE: To explore the impact of inflammatory factors on the incidence of cerebral small vessel disease (CSVD), we performed a mendelian randomization (MR) study to analyze the causal relationship between multiple inflammatory factors and CSVD imaging markers and utilized summary-data-based mendelian randomization (SMR) analysis to infer whether the impact of instrumental variables (IVs) on disease is mediated...

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• Share to Cerebrovascular and genetic disorders
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