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Article

Correlation between total homocysteine and cerebral small vessel disease: A Mendelian randomization study.

European journal of neurology - 1 Jun 2021

Cao Yuze, Su Ning, Zhang Dingding, Zhou Lixin, Yao Ming, Zhang Shuyang, Cui Liying, Zhu Yicheng, Ni Jun

Abstract excerpt

BACKGROUND AND PURPOSE: Cerebral small vessel disease (CSVD) is a clinical imaging syndrome with diverse etiology. Total homocysteine (HCY) level might increase the risk of myocardial and cerebral infarction by damaging the vascular endothelium. We aimed to explore the correlation between total HCY and CSVD imaging burden, based on Mendelian randomization methods. METHODS: A total of 1,023 participants of the...

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Identifiers

PMID: 33377242
DOI: 10.1111/ene.14708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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