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Article

Chromothripsis in myeloid malignancies.

Annals of hematology - 1 Oct 2024

Chen Chien-Yuan

Abstract excerpt

Chromothripsis refers to massive genomic rearrangements developed during a catastrophic event. In total acute myeloid leukemia (AML), the incidence of chromothripsis ranges from 0 to 6.6%, in cases of complex karyotype AML, the incidence of chromothripsis ranges from 27.3 to 100%, whereas in cases of AML with TP53 mutations, the incidence ranges from 11.1 to 90%. For other types of malignancies, the incidence of...

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Identifiers

PMID: 38814446
DOI: 10.1007/s00277-024-05814-9
PMCID: PMC11512916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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