Article
Novel insight into the genetic signatures of altitude adaptation related body composition in Tibetans.
Frontiers in public health - 1 Jan 2024
Li Xuguang, Xu Shilin, Li Xuemei, Wang Yuhe, Sheng Yemeng, Zhang Hengxun, Yang Wei, Yuan Dongya, Jin Tianbo, He Xue
Abstract excerpt
Background: The Tibetan population residing in high-altitude (HA) regions has adapted to extreme hypoxic environments. However, there is limited understanding of the genetic basis of body compositions in Tibetan population adapted to HA. Methods: We performed a genome-wide association study (GWAS) to identify genetic variants associated with HA and HA-related body composition traits. A total of 755,731 single...
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