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Article

Metabolic aspects of high-altitude adaptation in Tibetans.

Experimental physiology - 1 Nov 2015

Ge Ri-Li, Simonson Tatum S, Gordeuk Victor, Prchal Josef T, McClain Donald A

Abstract excerpt

NEW FINDINGS: What is the topic of this review? The topic of this review is how Tibetans have adapted genetically to high altitude, particularly with reference to altitude-induced changes in metabolism. What advances does it highlight? It highlights recent work on metabolic phenotyping in Tibetans and demonstrates that selected genetic haplotypes influence their metabolism of fats and glucose. Recent studies have...

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Source

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Identifiers

PMID: 26053282
DOI: 10.1113/EP085292
PMCID: PMC10905973

Genes

EGLN1
EPAS1
PPARA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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