Article
Correlation of DNA methylation patterns to the phenotypic features of Tibetan elite alpinists in extreme hypoxia.
Journal of genetics and genomics = Yi chuan xue bao - 20 Oct 2021
Basang Zhuoma, Zhang Shixuan, Yang La, Quzong Deji, Li Yi, Ma Yanyun, Hao Meng, Pu WeiLin, Liu Xiaoyu, Xie Hongjun, Liang Meng, Wang Jiucun, Danzeng Qiangba
Abstract excerpt
High altitude is an extreme environment that imposes hypoxic pressure on physiological processes, and natives living at high altitudes are more adaptive in certain physiological processes. So far, epigenetic modifications under extreme changes in hypoxic pressures are relatively less understood. Here, we recruit 32 Tibetan elite alpinists (TEAs), who have successfully mounted Everest (8848 m) at least five times....
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