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Article

Deep phenotyping of 11,880 highlanders reveals novel adaptive traits in native Tibetans

18 Aug 2023

Abstract excerpt

Tibetans are the ideal population to study genetic adaptation in extreme environments. Here, we performed systematic phenotyping of 11,880 highlanders, covering 133 quantitative traits of 13 organ systems. We provided a comprehensive phenotypic atlas by comparing altitude adaptation and altitude acclimatization. We found the differences between adaptation and acclimatization are quantitative rather than...

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PMID: 37680474
DOI: 10.1016/j.isci.2023.107677

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