Article
Differential interactions between gene expressions and stressors across the lifespan in major depressive disorder.
Journal of affective disorders - 1 Oct 2024
Wang Ruiyang, Su Yingying, O'Donnell Kieran, Caron Jean, Meaney Michael, Meng Xiangfei, Li Yue
Abstract excerpt
BACKGROUND: Both genetic predispositions and exposures to stressors have collectively contributed to the development of major depressive disorder (MDD). To deep dive into their roles in MDD, our study aimed to examine which susceptible gene expression interacts with various dimensions of stressors in the MDD risk among a large population cohort. METHODS: Data analyzed were from a longitudinal community-based...
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