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Article

JAK2V617F Mutation in Endothelial Cells of Patients with Atherosclerotic Carotid Disease

Turkish journal of haematology : official journal of Turkish Society of Haematology - 28 Aug 2024

Diz-Küçükkaya Reyhan, İyigün Taner, Albayrak Özgür, Eker Candan, Günel Tuba

Abstract excerpt

Objective: It has been shown that clonal mutations occur in hematopoietic stem cells with advancing age and increase the risk of death due to atherosclerotic vascular diseases, similarly to myeloproliferative neoplasms. Endothelial cells (ECs) and hematopoietic stem cells develop from common stem cells called hemangioblasts in the early embryonic period. However, the presence of hemangioblasts in the postnatal...

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Identifiers

PMID: 38801025
DOI: 10.4274/tjh.galenos.2024.2024.0161
PMCID: PMC11589362

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