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Article

Prevalence and Therapeutic Implications of Clonal Hematopoiesis of Indeterminate Potential in Young Patients With Stroke.

Stroke - 1 Apr 2023

Mayerhofer Ernst, Strecker Christoph, Becker Heiko, Georgakis Marios K, Uddin Md Mesbah, Hoffmann Michael M, Nadarajah Niroshan, Meggendorfer Manja, Haferlach Torsten, Rosand Jonathan, Natarajan Pradeep, Anderson Christopher D, Harloff Andreas, Hoermann Gregor

Abstract excerpt

BACKGROUND: Undetermined stroke etiology hampers optimal secondary prevention in a large proportion of young patients. We explored whether genetic screening for clonal hematopoiesis of indetermined potential (CHIP), a novel risk factor for stroke, could identify patients with myeloid precursor lesions or covert myeloid neoplasm requiring specific treatment. METHODS: We performed targeted sequencing on 56 genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36789775
DOI: 10.1161/STROKEAHA.122.041416
PMCID: PMC10050122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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