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Article

JAK2V617F mutation is highly prevalent in patients with ischemic stroke: a case-control study.

Blood advances - 10 Oct 2023

Kristiansen Marie Hvelplund, Kjær Lasse, Skov Vibe, Larsen Morten Kranker, Ellervik Christina, Hasselbalch Hans Carl, Wienecke Troels

Abstract excerpt

Ischemic stroke has a high recurrence rate despite treatment. This underlines the significance of investigating new possible cerebrovascular risk factors, such as the acquired gene mutation JAK2V617F found in 3.1% of the general population. We aimed to investigate the prevalence of the JAK2V617F mutation in a population with ischemic stroke compared with that in matched controls. We enrolled 538 consecutive...

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Identifiers

PMID: 37522722
DOI: 10.1182/bloodadvances.2023010588
PMCID: PMC10561044

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