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Identification of New Substrates and Inhibitors of Human CYP2A7.

Molecules (Basel, Switzerland) - 8 May 2024

Ashraf Rana Azeem, Liu Sijie, Wolf Clemens Alexander, Wolber Gerhard, Bureik Matthias

Abstract excerpt

CYP2A7 is one of the most understudied human cytochrome P450 enzymes and its contributions to either drug metabolism or endogenous biosynthesis pathways are not understood, as its only known enzymatic activities are the conversions of two proluciferin probe substrates. In addition, the CYP2A7 gene contains four single-nucleotide polymorphisms (SNPs) that cause missense mutations and have minor allele frequencies...

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Identifiers

PMID: 38792050
DOI: 10.3390/molecules29102191
PMCID: PMC11123773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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