Article
Polymorphisms of drug-metabolizing enzyme CYP2E1 in Chinese Uygur population.
Medicine - 1 Feb 2018
Zhu Linhao, He Yongjun, Niu Fanglin, Yan Mengdan, Li Jing, Yuan Dongya, Jin Tianbo
Abstract excerpt
Pharmacogenetics is the genetic basis of pharmacokinetics, genetic testing, and clinical management in diseases. Evaluation about genetic alterations of drug metabolizing enzymes in human genome contributes toward understanding the interindividual and interethnic variability for clinical response to potential toxicants. CYP2E1 gene encodes a drug-metabolizing enzyme that metabolizes mostly small, polar molecules,...
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