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Article

Constitutive type-1 interferons signaling activity in malignant gliomas.

Journal of neuro-oncology - 1 Jul 2024

Li Chunzhao, Long Lang, Wang Yi, Chi Xiaohan, Zhang Peng, Zhang Yang, Ji Nan

Abstract excerpt

PURPOSE: Recent studies revealed a pro-tumor effect of constitutive Type-1 interferons (IFN-I) production and the downstream signaling activity in several malignancies. In contrast, heterogeneity and clinical significance of the signaling activity in gliomas remain unknown. Thus, we aimed to depict the heterogeneity and clinical significance of constitutive Type-1 interferon (IFN-I) production and the downstream...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38789844
DOI: 10.1007/s11060-024-04601-w

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