Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interferon-beta inhibits human glioma stem cell growth by modulating immune response and cell cycle related signaling pathways

2 Jul 2022

Abstract excerpt

Malignant Glioma is characterized by strong self-renewal potential and immature differentiation potential. The main reason is that malignant glioma holds key cluster cells, glioma stem cells (GSCs). GSCs contribute to tumorigenesis, tumor progression, recurrence, and treatment resistance. Interferon-beta (IFN-β) is well known for its anti-proliferative efficacy in diverse cancers. IFN-β also displayed potent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Glioma Diagnosis and Treatment
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35778531
DOI: 10.1186/s13619-022-00123-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon-beta inhibits human glioma stem cell growth by modulating immune response and cell cycle related signaling pathwaysPMID 35778531Read ↗

Interferon-Beta Inhibits Human Glioma Stem Cells Rather Than Neural Stem Cells via Cell Cycle and Immune SignalingSemantic proximity Read ↗

The Interactions Between Cancer Stem Cells and the Innate Interferon Signaling PathwaySemantic proximity Read ↗

Interferon gamma-related gene signature based on anti-tumor immunity predicts glioma patient prognosisSemantic proximity Read ↗

Single-Cell RNA-Sequencing Shift in the Interaction Pattern Between Glioma Stem Cells and Immune Cells During TumorigenesisSemantic proximity Read ↗

Cancer Stem Cells and Immunosuppressive Microenvironment in GliomaSemantic proximity Read ↗

Construction of Interferon-Gamma-Related Gene Signature to Characterize the Immune-Inflamed Phenotype of Glioblastoma and Predict Prognosis, Efficacy of Immunotherapy and Radiotherapy.Semantic proximity Read ↗

Novel interferon-gamma-related 2-gene signature predicts outcome and responsiveness to immune checkpoint blockade in gliomaSemantic proximity Read ↗

IFN-γ Triggered IFITM2 Expression to Induce Malignant Phenotype in Elderly GBM.Semantic proximity Read ↗

Oncolytic herpes simplex viruses for the treatment of glioma and targeting glioblastoma stem-like cellsSemantic proximity Read ↗

Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cellsSemantic proximity Read ↗

ZEB1 regulates glioma stemness through LIF repressionSemantic proximity Read ↗

IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEADSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.