Article
NFAT1-regulated IL6 signalling contributes to aggressive phenotypes of glioma.
Cell communication and signaling : CCS - 19 Dec 2017
Jiang Yang, Han Sheng, Cheng Wen, Wang Zixun, Wu Anhua
Abstract excerpt
BACKGROUND: We previously demonstrated that the local immune status correlated with the glioma prognosis. Interleukin-6 (IL6) was identified as an important local immune-related risk marker related to unfavourable prognosis. In this study, we further investigated the role and regulation of IL6 signalling in glioma. METHODS: The expression and prognostic value of IL6 and the IL6 receptor (IL6R) were explored in...
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