Article
Integration of epidemiology, immunobiology, and translational research for brain tumors.
Annals of the New York Academy of Sciences - 1 May 2013
Okada Hideho, Scheurer Michael E, Sarkar Saumendra N, Bondy Melissa L
Abstract excerpt
We recently identified a pivotal role for the host type I interferon (IFN) pathway in immunosurveillance against de novo mouse glioma development, especially through the regulation of immature myeloid cells (IMCs) in the glioma microenvironment. The present paper summarizes our published work in a number of areas. We have identified single-nucleotide polymorphisms (SNPs) in human IFN genes that dictate altered...
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