Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Interferon regulatory factor transcript levels correlate with clinical outcomes in human glioma

26 Apr 2021

Abstract excerpt

Members of the interferon regulatory factor (IRF) gene family are crucial regulators of type I interferon signaling, which may play a role in the resistance of glioma to immune checkpoint blockade. However, the expression profiles, potential functions, and clinical significance of IRF family members remain largely unknown. Here, we examined IRF transcript levels and clinicopathological data from glioma patients...

Topics

Join the communities discussing this publication.

Cancer-related molecular mechanisms research
Glioma Diagnosis and Treatment
interferon and immune responses

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33902005
DOI: 10.18632/aging.202915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon regulatory factor transcript levels correlate with clinical outcomes in human gliomaPMID 33902005Read ↗

Interferon gamma-related gene signature based on anti-tumor immunity predicts glioma patient prognosisSemantic proximity Read ↗

IRF7 as an Immune-Related Prognostic Biomarker and Associated with Tumor Microenvironment in Low-Grade GliomaSemantic proximity Read ↗

The IRF family can influence tumor immunity and the prognosis of patients with colorectal cancerSemantic proximity Read ↗

TGIF2 is a potential biomarker for diagnosis and prognosis of glioma.Semantic proximity Read ↗

Interferon regulatory factor family influences tumor immunity and prognosis of patients with colorectal cancerSemantic proximity Read ↗

Constitutive type-1 interferons signaling activity in malignant gliomas.Semantic proximity Read ↗

Prognostic Significance of mRNA Expression RBBP8 or its Methylation in GliomasSemantic proximity Read ↗

Interferon Regulatory Factor 4 (IRF4) is a Prognostic Marker and Related to Immune Infiltration in Breast and Colorectal CancersSemantic proximity Read ↗

Interferon regulatory factor family of transcription factors and regulation of oncogenesis.Semantic proximity Read ↗

Role of interferon regulatory factor 5 (IRF5) in tumor progression: Prognostic and therapeutic potentialSemantic proximity Read ↗

Molecular and clinical features of a potential immunotherapy target ELK3 in gliomaSemantic proximity Read ↗

Novel interferon-gamma-related 2-gene signature predicts outcome and responsiveness to immune checkpoint blockade in gliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.