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Article

In vitro generation of genetic diversity for directed evolution by error-prone artificial DNA synthesis.

Communications biology - 24 May 2024

Wang Baowei, Liu Yang, Bai Xuelian, Tian Huijuan, Wang Lina, Feng Miao, Xia Hairong

Abstract excerpt

Generating genetic diversity lies at the heart of directed evolution which has been widely used to engineer genetic parts and gene circuits in synthetic biology. With the ever-expanding application of directed evolution, different approaches of generating genetic diversity are required to enrich the traditional toolbox. Here we show in vitro generation of genetic diversity for directed evolution by error-prone...

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Identifiers

PMID: 38789612
DOI: 10.1038/s42003-024-06340-0
PMCID: PMC11126579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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