Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Enhancing Cellular and Enzymatic Properties Through In Vivo Continuous Evolution.

Chembiochem : a European journal of chemical biology - 16 Dec 2024

Chu Weiran, Guo Yaxin, Wu Yaokang, Lv Xueqin, Li Jianghua, Liu Long, Du Guocheng, Chen Jian, Liu Yanfeng

Abstract excerpt

Directed evolution seeks to evolve target genes at a rate far exceeding the natural mutation rate, thereby endowing cellular and enzymatic properties with desired traits. In vivo continuous directed evolution achieves these purposes by generating libraries within living cells, enabling a continuous cycle of mutant generation and selection, enhancing the exploration of gene variants. Continuous evolution has...

Topics

Directed Molecular Evolution
Mutation
Enzymes
Mutagenesis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39248206
DOI: 10.1002/cbic.202400564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancing Cellular and Enzymatic Properties Through In Vivo Continuous Evolution.PMID 39248206Read ↗

The developing toolkit of continuous directed evolution.Semantic proximity Read ↗

Advances in in vivo continuous evolution technologies for strain development and enzyme engineering.Semantic proximity Read ↗

Systems for in vivo hypermutation: a quest for scale and depth in directed evolution.Semantic proximity Read ↗

[Recent advances of continuous in vivo evolution].Semantic proximity Read ↗

In vivo hypermutation and continuous evolutionSemantic proximity Read ↗

Empowering continuous evolution of proteins by in vivo mutagenesis.Semantic proximity Read ↗

The evolving art of creating genetic diversity: From directed evolution to synthetic biology.Semantic proximity Read ↗

[Progress in the construction and screening of random mutation library].Semantic proximity Read ↗

Directed genome evolution driven by structural rearrangement techniques.Semantic proximity Read ↗

Polishing the craft of genetic diversity creation in directed evolution.Semantic proximity Read ↗

Genetic engineering: CREATE-ing genome-wide designed mutations.Semantic proximity Read ↗

Man-made enzymes--from design to in vitro compartmentalisation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.