Article

Fibroblasts dynamically regulate lymphatic barrier function by modulating cell-cell junctions

2025-04-23

Abstract excerpt

<h4>ABSTRACT</h4> Lymphatic dysfunction has been linked to several pathological conditions, including edema, inflammation, and cancer metastasis. The tight and adherens junction proteins between lymphatic endothelial cells (LECs) are important for preserving lymphatic vascular integrity. Despite the known role of fibroblasts in lymphangiogenesis, the direct impact of fibroblasts on LEC barrier function remains po...

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Literature Corpus work: d6de924d-f4bc-510c-a4ce-fc04c1c6bac9
DOI: 10.1101/2025.04.17.649442

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