Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The pluripotency factor NANOG contributes to mesenchymal plasticity and is predictive for outcome in esophageal adenocarcinoma

17 May 2024

Abstract excerpt

BACKGROUND: Despite the advent of neoadjuvant chemoradiotherapy (CRT), overall survival rates of esophageal adenocarcinoma (EAC) remain low. A readily induced mesenchymal transition of EAC cells contributes to resistance to CRT. METHODS: In this study, we aimed to chart the heterogeneity in cell state transition after CRT and to identify its underpinnings. A panel of 12 esophageal cultures were treated with CRT...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Esophageal Cancer Research and Treatment
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38760583
DOI: 10.1038/s43856-024-00512-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The pluripotency factor NANOG contributes to mesenchymal plasticity and is predictive for outcome in esophageal adenocarcinomaPMID 38760583Read ↗

Neoadjuvant therapy-associated malignant phenotype score predicts prognosis and highlights the roles of MIF signaling and DUXAP8 in ESCC.Semantic proximity Read ↗

Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinomaSemantic proximity Read ↗

Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of esophageal adenocarcinomaSemantic proximity Read ↗

Transcriptomic-Based Quantification of the Epithelial-Hybrid-Mesenchymal Spectrum across Biological ContextsSemantic proximity Read ↗

Transcriptomic-based quantification of the epithelial-hybrid-mesenchymal spectrum across biological contextsSemantic proximity Read ↗

Translational control of breast cancer plasticitySemantic proximity Read ↗

The pluripotency factor NANOG promotes the formation of squamous cell carcinomasSemantic proximity Read ↗

ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomas.Semantic proximity Read ↗

NRF2 pathway activation and SPP1⁺TREM2⁺ macrophages drive chemoradiotherapy resistance in esophageal squamous cell carcinomaSemantic proximity Read ↗

Machine Learning–Guided Differentiation Therapy Targets Cancer Stem Cells in Colorectal CancersSemantic proximity Read ↗

NANOG Promotes Cell Proliferation, Invasion, and Stemness via IL-6/STAT3 Signaling in Esophageal Squamous CarcinomaSemantic proximity Read ↗

NANOG: A promising target for digestive malignant tumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.