Article
The effect of IL-1R1 and IL-1RN polymorphisms on osteoporosis predisposition in a Chinese Han population.
International immunopharmacology - 1 Oct 2020
Zhang Lei, Zhou Qianyu, Wu Zhihui, Zhu Xin, Geng Tongyu
Abstract excerpt
BACKGROUND: Osteoporosis (OP) is a common inflammatory disease. The goal of this study was to investigate the effect of IL-1R1 and IL-1RN polymorphisms on OP predisposition among the Chinese Han population. METHODS: Six single nucleotide polymorphisms (SNPs) in IL-1R1 and IL-1RN were genotyped using the Agena MassARRAY platform in 594 OP patients and 599 age- and sex- matched healthy controls. Logistic regression...
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