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Article

Association between circulating inflammatory proteins and gout: A Mendelian randomization study.

Medicine - 16 May 2025

Xie Xiaochao, Song Yanjie, Chen Wenwen, Zhao Hui, Chu Nan, Wang Fang

Abstract excerpt

Clinical studies have consistently demonstrated that inflammation is a critical factor in the pathophysiology and progression of gout. This study aims to explore the causal relationship between CIPs and gout, utilizing MR in conjunction with meta-analyses. We utilized genetic data pertaining to gout from the GWAS which involved 3576 cases and 147,221 control participants. A total of 132 CIPs were extracted from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40388724
DOI: 10.1097/MD.0000000000042379
PMCID: PMC12091660

Genes

CXCL1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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