Article

SMuRF: a novel tool to identify genomic regions enriched for somatic point mutations

2018-02-26

Abstract excerpt

<h4>Motivation</h4> Single Nucleotide Variants (SNVs), including somatic point mutations and Single Nucleotide Polymorphisms (SNPs), in noncoding cis-regulatory elements (CREs) can affect gene regulation and lead to disease development (Zhou et al. , 2016; Zhang et al. , 2014). Others have previously developed methods to identify important clusters of somatic point mutations based on proximity (Weinhold et al....

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Literature Corpus work: cdd863ad-e703-5808-afa4-c1a4b9c27351
DOI: 10.1101/271957

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