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DNA Methylation in the Anti-Mullerian Hormone Gene and the Risk of Disease Activity in Multiple Sclerosis.

Annals of neurology - 1 Aug 2024

Giordano Antonino, Pignolet Béatrice, Mascia Elisabetta, Clarelli Ferdinando, Sorosina Melissa, Misra Kaalindi, Bucciarelli Florence, Ferrè Laura, Moiola Lucia, Liblau Roland, Filippi Massimo, Esposito Federica

Abstract excerpt

OBJECTIVE: Multiple sclerosis (MS) has a complex pathobiology, with genetic and environmental factors being crucial players. Understanding the mechanisms underlying heterogeneity in disease activity is crucial for tailored treatment. We explored the impact of DNA methylation, a key mechanism in the genetics-environment interplay, on disease activity in MS. METHODS: Peripheral immune methylome profiling using...

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PMID: 38747444
DOI: 10.1002/ana.26959

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AMH
CIT
EDA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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