Experimental Evaluation of a Direct Fitness Effect of the De Novo Evolved Mouse Gene Pldi.

Abstract excerpt

De novo evolved genes emerge from random parts of noncoding sequences and have, therefore, no homologs from which a function could be inferred. While expression analysis and knockout experiments can provide insights into the function, they do not directly test whether the gene is beneficial for its carrier. Here, we have used a seminatural environment experiment to test the fitness of the previously identified de...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bayes Theorem
• Share to Evolution, Molecular