Article
Genome-wide association for testis weight in the diversity outbred mouse population.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2018
Yuan Joshua T, Gatti Daniel M, Philip Vivek M, Kasparek Steven, Kreuzman Andrew M, Mansky Benjamin, Sharif Kayvon, Taterra Dominik, Taylor Walter M, Thomas Mary, Ward Jeremy O, Holmes Andrew, Chesler Elissa J, Parker Clarissa C
Abstract excerpt
Testis weight is a genetically mediated trait associated with reproductive efficiency across numerous species. We sought to evaluate the genetically diverse, highly recombinant Diversity Outbred (DO) mouse population as a tool to identify and map quantitative trait loci (QTLs) associated with testis weight. Testis weights were recorded for 502 male DO mice and the mice were genotyped on the GIGAMuga array at...
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