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Article

Mouse models of human evolution.

Current opinion in genetics & development - 1 Dec 2014

Enard Wolfgang

Abstract excerpt

The genotype-phenotype map of human evolution is difficult to access since humans cannot be crossed with other species. Most of the ∼20 million genetic changes that occurred since the human and the chimpanzee lineage split, are fixed and hence completely correlated with all phenotypic changes that occurred during human evolution. While patterns of selection and functional information on genomic regions are...

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PMID: 25218860
DOI: 10.1016/j.gde.2014.08.008

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Source receipt: pubmed, retrieved 7 Sept 2026.

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