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Epidemiological and molecular evaluation of BRAF, KRAS, NRAS genes and MSI in the development of colorectal cancer.

Gene - 20 Jun 2023

Paula Simedan Vila Ana, Helena Rodrigues Gabriela, Leite Marzochi Ludmila, Garcia de Oliveira-Cucolo Juliana, Lívia Silva Galbiatti-Dias Ana, Felipe Maciel Andrade Rafael, de Santi Neto Dalísio, Gomes Netinho João, Castiglioni Lilian, Cristina Pavarino Érika, Maria Goloni-Bertollo Eny

Abstract excerpt

BACKGROUND AND OBJECTIVES: KRAS, NRAS, BRAF mutations and microsatellite instability (MSI) can be associated with Colorectal Cancer (CRC) development. MATERIAL AND METHODS: We evaluated 828 medical records of CRC patients from a school hospital from January/2016 to December/2020. Variables such as age, gender, ethnicity, literacy level, smoking, alcoholism, primary anatomical site, tumor staging, presence of...

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PMID: 36990254
DOI: 10.1016/j.gene.2023.147395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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