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Article

KRAS, NRAS and BRAF Mutational Landscape in Serbian Early-Onset Colorectal Cancer Patients.

Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2026

Despotović Jovana, Nikolić Neda, Babic Tamara, Ugrin Milena, Rom Aleksandra Đikić, Damjanović Ana, Nikolic Aleksandra, Dragičević Sandra

Abstract excerpt

IntroductionEarly-onset colorectal cancer (EOCRC) is increasing worldwide, with Serbia showing a similar incidence compared to global trends. Precise mutation genotyping has gained importance following the recent approval of KRAS-specific inhibitors. Although KRAS, NRAS, and BRAF testing is routinely performed in Serbia, specific mutation subtypes in EOCRC patients have not yet been published. This retrospective...

Topics

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Age of Onset
Colorectal Neoplasms
GTP Phosphohydrolases
Incidence
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins B-raf

Proto-Oncogene Proteins p21(ras)

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Open in PubMed Open full text

Identifiers

PMID: 41719060
DOI: 10.1177/10732748261426049
PMCID: PMC12925009

Genes

KRAS
BRAF
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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