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Article

Mutation characteristics and molecular evolution of ovarian metastasis from gastric cancer and potential biomarkers for paclitaxel treatment.

Nature communications - 4 May 2024

Yu Pengfei, Hu Can, Ding Guangyu, Shi Xiaoliang, Xu Jingli, Cao Yang, Chen Xiangliu, Wu Wei, Xu Qi, Fang Jingquan, Huang Xingmao, Yuan Shaohua, Chen Hui, Wang Zhizheng, Huang Ling, Pang Fei, Du Yian, Cheng Xiangdong

Abstract excerpt

Ovarian metastasis is one of the major causes of treatment failure in patients with gastric cancer (GC). However, the genomic characteristics of ovarian metastasis in GC remain poorly understood. In this study, we enroll 74 GC patients with ovarian metastasis, with 64 having matched primary and metastatic samples. Here, we show a characterization of the mutation landscape of this disease, alongside an...

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Identifiers

PMID: 38704377
DOI: 10.1038/s41467-024-48144-0
PMCID: PMC11069556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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