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A comprehensive approach to evaluate genetic abnormalities in multiple myeloma using optical genome mapping

3 May 2024

Abstract excerpt

Multiple myeloma (MM) is a plasma cell neoplasm (PCN) [ 1 ]. Sensitive and accurate identification of genetic abnormalities is critical for patient risk stratification and therapeutic decision-making as well as understanding pathogenesis. Recurring genetic abnormalities include structural variants (SVs), such as rearrangements involving IGH and MYC genes; copy number variants (CNVs), such as 1q+, del(17p),...

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PMID: 38702349
DOI: 10.1038/s41408-024-01059-x

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