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Optical Genome Mapping Reveals the Complex Genetic Landscape of Myeloma

22 Sept 2023

Abstract excerpt

Fluorescence in situ hybridization (FISH) on enriched CD138 plasma cells is the standard method for identification of clinically relevant genetic abnormalities in multiple myeloma. However, FISH is a targeted analysis that can be challenging due to the genetic complexity of myeloma. The aim of this study was to evaluate the potential of optical genome mapping (OGM) to detect clinically significant cytogenetic...

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PMID: 37835381
DOI: 10.3390/cancers15194687

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