Article
The Evolving Role of Genomic Technologies in Multiple Myeloma: Implications for Diagnosis, Risk Stratification and Resistance.
Molecular diagnosis & therapy - 1 May 2026
Baďurová Klára, Kapustová Veronika, Kotulová Jana, Brinsa Vítězslav, Piherová Lenka, Janoušek Václav, Pohludka Michal, Richtář Michal, Jelínek Tomáš, Hájek Roman, Chyra Zuzana, Ševčíková Tereza
Abstract excerpt
Plasma cell disorders range from indolent precursors to aggressive malignancies, with multiple myeloma as the most common malignant form. Multiple myeloma biology is highly complex and driven by genomic heterogeneity. Although recent genomic advances offer increasingly precise treatment strategies, routinely used conventional diagnostic methods sometimes fail to reflect the evolution of up-to-date multiple...
Topics
- Humans
- Multiple Myeloma
- Genomics
- Risk Assessment
- Drug Resistance, Neoplasm
- Biomarkers, Tumor
- Mutation
- Genetic Predisposition to Disease