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Article

Genetic and epigenetic heterogeneity and the impact on cancer relapse.

Experimental hematology - 1 Oct 2017

Hassan Ciaran, Afshinnekoo Ebrahim, Li Sheng, Wu Shixiu, Mason Christopher E

Abstract excerpt

Acute myeloid leukemia (AML) is an aggressive hematopoietic malignancy with an exceedingly poor prognosis: a 5-year overall survival rate of 40%-45% in the young and a 5-year survival rate of less than 10% in the elderly (>60 years of age). Although a high percentage of patients enters complete remission after chemotherapeutic intervention, the majority of patients relapse within 3 years. Such stark prognostic...

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Identifiers

PMID: 28705639
DOI: 10.1016/j.exphem.2017.07.002
PMCID: PMC5651672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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