Article
Allogeneic Hematopoietic Cell Transplantation in Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Genetic Features: Relevance of the Genetic Underlying Category. A Retrospective Analysis on Behalf of the Acute Leukemia Working Party of the EBMT.
American journal of hematology - 1 Jun 2025
Esteve Jordi, Nagler Arnon, Labopin Myriam, Versluis Jurjen, Sanz Jaime, Gedde-Dahl Tobias, Burns David, Roeven Mieke, Labussière-Wallet Hélène, von dem Borne Peter, van Gorkom Gwendolyn, Contentin Nathalie, Neubauer Andreas, Wagner-Drouet Eva Maria, Kröger Nicolaus, Mohty Mohamad, Ciceri Fabio
Abstract excerpt
Patients (pts) with myelodysplasia-related AML (MR-AML) are now genetically recategorized, with three different groups in the International Consensus Classification: AML with mutated TP53 (TP53-AML), with myelodysplasia-related gene mutations (MR-GM AML), and with myelodysplasia-related cytogenetic abnormalities (MR-CG AML). Moreover, TP53-AML is determined by the presence of an additional complex karyotype...
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