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Article

Associations of combined phenotypic aging and genetic risk with incident cancer: A prospective cohort study.

eLife - 30 Apr 2024

Bian Lijun, Ma Zhimin, Fu Xiangjin, Ji Chen, Wang Tianpei, Yan Caiwang, Dai Juncheng, Ma Hongxia, Hu Zhibin, Shen Hongbing, Wang Lu, Zhu Meng, Jin Guangfu

Abstract excerpt

Background: Age is the most important risk factor for cancer, but aging rates are heterogeneous across individuals. We explored a new measure of aging-Phenotypic Age (PhenoAge)-in the risk prediction of site-specific and overall cancer. Methods: Using Cox regression models, we examined the association of Phenotypic Age Acceleration (PhenoAgeAccel) with cancer incidence by genetic risk group among 374,463...

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Identifiers

PMID: 38687190
DOI: 10.7554/eLife.91101
PMCID: PMC11060710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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