Article
Impact of accelerated biological aging and genetic variation on esophageal adenocarcinoma: Joint and interaction effect in a prospective cohort.
International journal of cancer - 15 Jan 2025
Zhao Renjia, Yuan Huangbo, Chen Shuaizhou, Xu Kelin, Zhang Tiejun, Liu Zhenqiu, Jiang Yanfeng, Suo Chen, Chen Xingdong
Abstract excerpt
Accelerated biological aging may be associated with increased risk of esophageal adenocarcinoma (EAC). However, its relationship with genetic variation, and its effect on improving risk population stratification, remains unknown. We performed an exposome association study to determine potential associated factors associated with EAC. To quantify biological age and its difference from chronological age, we...
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