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Altered Plasma Levels and Tissue Expression of Fibroblast Activation Protein Alpha in Giant Cell Arteritis

30 Apr 2024

Abstract excerpt

Objective Giant cell arteritis (GCA) is characterized by granulomatous inflammation of the medium‐ and large‐sized arteries accompanied by remodeling of the vessel wall. Fibroblast activation protein alpha (FAP) is a serine protease that promotes both inflammation and fibrosis. Here, we investigated the plasma levels and vascular expression of FAP in GCA. Methods Plasma FAP levels were measured with enzyme‐linked...

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PMID: 38685696
DOI: 10.1002/acr.25354

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