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Article

GSTP1 and ABCB1 Polymorphisms Predicting Toxicities and Clinical Management on Carboplatin and Paclitaxel-Based Chemotherapy in Ovarian Cancer.

Clinical and translational science - 1 Mar 2021

Ferracini Amanda Canato, Lopes-Aguiar Leisa, Lourenço Gustavo Jacob, Yoshida Adriana, Lima Carmen Silva Passos, Sarian Luis Otávio, Derchain Sophie, Kroetz Deanna L, Mazzola Priscila Gava

Abstract excerpt

Variation in drug disposition genes might contribute to susceptibility to toxicities and interindividual differences in clinical management on chemotherapy for epithelial ovarian cancer (EOC). This study was designed to explore the association of GST and ABCB1 genetic variation with hematologic and neurologic toxicity, changes in chemotherapy, and disease prognosis in Brazilian women with EOC. A total of 112...

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Share to Carboplatin
Share to Carcinoma, Ovarian Epithelial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemotherapy, Adjuvant

Share to Neoadjuvant Therapy

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Source

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Identifiers

PMID: 33326171
DOI: 10.1111/cts.12937
PMCID: PMC7993324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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